Tris buffer (THAM). An appraisal of its physiologic effects and clinical usefulness.
|Title||Tris buffer (THAM). An appraisal of its physiologic effects and clinical usefulness.|
|Publication Type||Journal Article|
|Year of Publication||1966|
|Authors||Bleich HL, Schwartz WB|
|Journal||N Engl J Med|
|Date Published||1966 Apr 07|
|Keywords||Acidosis, Acidosis, Respiratory, Acids, Blood Preservation, Buffers, Citric Acid, Glucose, Humans, Poisoning, Tromethamine|
It has been the purpose of this discussion to review critically the physiologic considerations and clinical evidence regarding the use of Tris buffer in the treatment of acid-base disorders. It is concluded that there is little current evidence, theoretical, experimental, or clinical, to support the view that Tris has a significant therapeutic role. Some possible exceptions to this general conclusion are considered.
|Alternate Journal||N Engl J Med|
|Grant List||H-759 / / PHS HHS / United States |
HE 5309 / / PHS HHS / United States